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New Research on PSSD: Mechanisms, Treatments & More

Lucas Aoun discusses the mechanisms, treatments, and research surrounding post SSRI sexual dysfunction (PSSD), a condition that can occur after discontinuing use of SSRI medications.

Post SSRI Sexual Dysfunction PSSD Mechanisms, Treatments & Research By Lucas Aoun

In this episode, we speak with Dr. Lucas Aoun, a medical doctor and researcher specializing in the treatment of post-SSRI sexual dysfunction (PSSD). Dr. Aoun discusses the mechanisms of PSSD, treatments that have been found to be effective, and ongoing research into this condition. He also describes how PSSD can impact every aspect of a person’s life and offers advice for those struggling with this condition.

What is PSSD?

Post-SSRI sexual dysfunction (PSSD) is a condition that can occur after someone takes a selective serotonin reuptake inhibitor (SSRI) antidepressant. PSSD is characterized by the persistence of sexual side effects after discontinuing the SSRI, such as loss of libido, erectile dysfunction, and anorgasmia. PSSD can also cause emotional distress and can negatively impact every aspect of a person’s life.

What are the mechanisms of PSSD?

The exact mechanisms of PSSD are not fully understood, but it is thought to be caused by changes in the brain that occur as a result of taking an SSRI. These changes can include alterations in neurotransmitter levels, changes in gene expression, and changes in the structure and function of brain cells.

What treatments are available for PSSD?

There is no cure for PSSD, but there are treatments that can help alleviate the symptoms. These treatments include hormone therapy, sexual counseling, and medications to treat underlying conditions such as anxiety and depression.

What research is being done on PSSD?

There is currently no cure for PSSD, but researchers are working to better understand the condition and develop effective treatments. Studies have shown that PSSD is a real and debilitating condition that can have a profound impact on a person’s life. Current research is focused on identifying the mechanisms of PSSD and developing effective treatments.

Advice for those with PSSD

If you are struggling with PSSD, it is important to seek help from a healthcare professional who is familiar with the condition. There are treatments available that can help alleviate the symptoms of PSSD, but it is important to remember that there is no cure. PSSD can be a difficult condition to deal with, but it is important to remember that you are not alone.

In this episode, Lucas discusses a condition which impacts MILLIONS of people worldwide. Some of the symptoms of PSSD include: Weak orgasm, delayed orgasm, premature ejaculation, vaginal dryness, reduced pleasure, and reduced rewards. Lucas highlights potential theories, interventions, treatments and probes to unlock and help contribute to finding a cure in this space.

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Video transcription:

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What users commented:

PSSD ruined my life. I’m happy you’re looking for answerers. My doctors don’t even care.