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Erectile Dysfunction: The Most Effective Treatments Available

Erectile Dysfunction can be a difficult problem to deal with, but there are treatments available. Check out this article to learn more about the best treatments for ED, and how they can help you.

Erectile Dysfunction: The Best Available Treatments

Erectile dysfunction (ED), also known as impotence, is a type of sexual dysfunction characterized by the inability to develop or maintain an erection of the penis during sexual activity. ED can have psychological consequences as it can be tied to relationship difficulties and self-image. The best available treatments for ED are psychological counseling and sexual therapy. These therapies can help men and their partners cope with the psychological effects of ED. In addition, there are several effective oral and topical treatments that can improve the quality of a man’s erection. Oral treatments for ED include:
  • Sildenafil (Viagra)
  • Tadalafil (Cialis)
  • Vardenafil (Levitra, Staxyn)
  • Avanafil (Stendra)
Topical treatments for ED include:
  • Alprostadil (Caverject, Edex, MUSE)
  • Bimix and trimix (two and three drugs, respectively)
In addition to oral and topical treatments, there are other options for treating ED, such as:
  • Penile implants
  • Vacuum pumps
  • Injections
  • Hormone therapy
  • Blood vessel surgery
ED is a common problem, and there are many effective treatments available. If you are struggling with ED, talk to your doctor about the best treatment option for you.
The best Erectile Dysfunction treatment options with Kristine Clements ARNP-C

Invigor Podcast:…


Trimix Injections –…

PT-141 –…

Oxytocin –…


Kristine Clements


James Timmons –…

Savannah Webb


0:54 Causes of ED

2:21 When does ED Usually Start

3:45 Who can get ED?

4:17 Can ED be cured?

6:40 Injectable ED Medications: Trimix, Bimix, Quadmix

9:04 Do Penile Injections Hurt?

11:37 What do patients say?

12:21 What is the success rate of Trimix?

13:43 Oral ED Options: Cialis, Viagra

15:04 Side effects of Penile Injections: Trimix

16:24 Treatments for Libido: PT-141, Oxytocin

18:55 Oxytocin Spray

20:15 Stackable Medications: PT-141, Oxytocin

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Video transcription:

Savannah: Hello, everyone.
Welcome to Invigor Podcast., I’m, Savannah, Webb joined by James
Timmons, and today we are joined with Christine Clements,, who is
an ARNP-C and specializes in erectile, dysfunction. How are
you, doing today, Kristine? Kristine: I’m well, thank you
for having me. Savannah: Yeah, definitely.
James,. If you want to kind of maybe talk about what we’re
going to be going into. Today. James:, Yeah., So today, we’re
going, to be discussing everything from the causes: of
erectile dysfunction to the best available, treatments. So
Kristine,, educating ourselves in these things, is important. So we
want to spend the next few minutes. Having you help us
understand a few things about erectile dysfunction. So, what is
the science behind ED? Like? What is physically happening in the
body? Kristine: Typically, it’s
multifactorial. So. There is some vascularity resistance going on,
whether, that’s from diabetes, high blood pressure, can be from
high, cholesterol. Could be other things;. Maybe they have pelvic
fractures, or they’ve had, you know, paralysis of some sort.
Maybe. They have Parkinson’s disease or neurological issues.
And. So it can be a variety of reasons. Savannah: Can, you maybe talk
about. Some of the main causes of erectile dysfunction?, Kristine: The main causes that
we mostly see, are diabetes and high blood pressure, and
obesity. Savannah: Obesity, is that, how
does obesity play into erectile dysfunction? Does that have to
tie in with the vascular sort of issue with it or… Kristine: anytime, you have extra
weight,, you are taxing your body in some way. Whether, that’s on
your heart or your lungs,, and it does affect vascularity. James: Yeah,. We saw how obesity
affected people with like, during COVID and stuff. I mean,
yeah,, just overall,. It can definitely… it’s pretty common
knowledge that obesity affects just about everything, but it’s
interesting how it plays into erectile dysfunction. Yeah, how
would…. How would you… how common is erectile, dysfunction? Kristine: Yeah,, the numbers
about, how common it is, is hard to find, really,, because a lot
of patients and people don’t seek treatment. So they’re
embarrassed,. They don’t go to their doctor and talk about it.
And, so they just kind of suffer in silence.. But I would say,
from the best that we know,. Probably it affects 50% of our
men, 40 and up. James: Okay. Okay, I, just turned
40, so… clock is ticking. Kristine: where to go. Savannah: Maybe. Can. You tell us
a little bit about;. Is there any misconceptions about erectile
dysfunction that you hear a lot about? Kristine: Well,? What I would say
is that patients think that there is nothing that can be
“I just have this
“, you know,
“I cannot
“, you know,
relations, with my wife, with my girlfriend, with my partner…

and. There was nothing that we can do
“. But I would say. The
Majority of the time we can treat erectile dysfunction
successfully with a variety of ways. Savannah: Wow., Very, interesting.
Um,, yeah, that’s…, you know,! It’s what definitely one of
those, maybe more sensitive sort of health issues where I feel
like people might be a little bit more reluctant to come
forward and… and talk about it and admit that it’s an issue
that they’re having,, where it’s… it’s really, it’s
something. That doesn’t seem to be quite that way. Anybody can
be affected by it, Right? Different different risk, factors
and things like that., So, …, James: Yeah,. So you don’t have
the ability to like, just see somebody walking down the street
and that they’re suffering from erectile dysfunction. Kristine: That that is, you
know,. That is so funny because I have patients that are marathon
runners, triathletes, that are the epitome of health, and they
suffer from ED. So. It is not just, you know,, sometimes we
don’t know the reason. James: Yeah. Kristine: Which can be so
frustrating.. James: But, you know, the key to
the solution. Kristine: We do James: The treatment. Kristine: We definitely can help
most of our men,, which is great. James: Yeah,, so I mean, next
question… get closer into that; Can ED be cured?, Kristine: Sure., James:, Okay Kristine: It can be cured,
absolutely! If. It is multifactor,. Patients get their
blood pressure under control,, their cholesterol, down, their
body weight within normal limits. They can have ED issues
and. Then, all of a sudden you know, they’re functioning at
full capacity and doing fine. So. They either get off meds all…
you know,, all together and they’re able to perform and
function as they normally would.. Savannah: I want to talk about a
little bit more about the the treatments,, the actual
treatments of erectile dysfunction and how you were
saying it can be cured. ,. What can you tell us about? Maybe some
over the counter options: available? Kristine: Over, the counter
options? Not, so much, those are Can. You go a little bit more
into those two options that you gimmicky;: don’t really do
anything, except for take your money. Now,. There are some
things that they can do like wave therapy,, which is
ultrasound, frequencies, treatments. They’re expensive,
and. They often don’t last for talked about? very long. So. The longevity of
those treatments are not there.. Yeah. So there,, there’s a couple
of different ways to give both But. That is something that is
non invasive, that patients can maybe seek if they don’t want to
take medications. And supplements like arginine,
carnitine,, both of those can of those,. Those are amino. Acid
Blends. They can be given help with vascularity too. topically like on the inner
thigh. And, so they then absorbed systemically that way and help
with blood flow in the pelvic region. And. So they just take
that, or put that on their inner thigh before…. Before sex.
Also, they can use an injectable, and they come as an
injectable. And. You use that, you know, on a weekly basis, to
help as well. James: So. You say the word
injectable. and I already know the answer to this,, but I know
that. When men listen to that they shutter. So. Can you tell us
a little bit more about how the injectables work? Like what
exactly does that mean? Kristine: Sure, yeah. So when
oral medications are not effective, or they’re, not an
option,, because maybe you’re on other blood pressure medicines,
and they just don’t jive well. Together. We have something like
an injectable, a penile injectable,, which is either
bimix, trimix or quadmix. Based on the severity of of their
erectile dysfunction. There. Isn’t a lot of nerve, endings, on
the side of the shaft, where you give the injection, most of our
patients are quite comfortable. They, don’t even feel it. It is
just getting over the psychological part of
“oh my
gosh,. What am I getting into?, giving myself an injection?
“, James:, Yeah, and I know that,
that anyone that doesn’t know, they’re, probably imagining a
long needle. So. Can you tell us a little bit about just, what
that? What that needle looks like? Kristine:, I, can., This, syringes
are tiny,? They are the tuberculin,, what we call insulin
syringes; very small,, tiny, engage. So their,, their diameter
is, very small, and they’re just such that they get into the
cavernous body into the penile shaft, where the medication goes,
and, then that will cause the relaxation and the blood flow to
create. The erection. Savannah: You talked a little
bit about the bimix and trimix. Can. You maybe explain the
difference between those two different medications? Kristine: Sure. So, based on the
severity of a man’s erectile dysfunction,, the provider will
determine. What medication would be best for them., Trimix, is
three ingredients, bimix is two,. Quadmix is four. And, so like I
said, based on their age and their s everity,, the provider
would then recommend which level of treatment they would need.
Bimix. Often is, you know, reserved for less severe ED, or
ones that have some sort of sensitivity to an Alprostadil
which is a medication in the injectable. And quad mix, then
we reserve for patients that are older or some that need some
help with scar tissue breakup, with atropine in that mix. Can
Help do that for them. Savannah: And each of these, I
don’t assume it would be much difference. They’re all an
injection,, but do any of them,. What are your clients say? About
How it feels? Does it really hurt? And. Is this one of the
main things that causes them to maybe not go for this option, or Kristine: Once. They have made
the decision to try an injectable, a lot of times
they’ve done their doctor, Google, and researched, and have
really… I think the patients that come and wanted to do the
injectable, they’ve done a lot of research. And like I
mentioned before,. There’s not a lot of nerve endings on the side
of, the shaft. So. Most of them are quite comfortable., They
usually call us back and say,
“Oh,. You were right. It didn’t
it didn’t hurt
“. Because. If it hurt that would… they would
not want to do. It., Now,, I’m, just gonna be done. James: Yeah,, it’s funny. You
mentioned. They all did probably do a lot of research because I’m
imagining like yeah, I, don’t think I would like just walk
into a room. Like, okay, stick me. Yeah,, so there’s probably
like emotional barriers. They have to go through to get to
that, point., And, they’re, like, Okay, and it’s like, not as bad
as. They expected, You, know?, Kristine: Yeah, and a lot of
times they’ve. All they come to us because their friend or their
brother in law, or their father in law, or somebody has used it,
and. They have heard about it; From somebody they know and they
trust,, and that is big because nobody,, you know, better to
learn from… somebody know and trust. James: For sure. Yeah. So do you
know anything about homeopathic treatments?, Kristine:, Homeopathic
treatments? Are, you specifically asking about drops and that sort
of thing: or…? James:, Sure,, Yes., Kristine:, I, know of no
homeopathic treatments, that… James:, Okay., Okay., Kristine:, Honestly., Yeah., James:, Okay., Kristine:, I’m, sure they sell
them somewhere,, but I am not.. There is a injectable, or excuse
me. intra-urethral suppository. So. You basically stick a
urethral suppository… In, which case, it’s an alprostadil, but I
have not heard that it works very effectively, and it also
burns and hurts. James: The only place I welcome
any suppositories into my mouth. Like I, wouldn’t put an actual
suppository in my mouth. But… yeah, urethral suppository
sounds like a nightmare. Kristine: Most patients think…
yeah,, it’s a nightmare., Yeah. Savannah: Kristine, is there, I
want to I want to go on back on the topic of the trimix and
bimix injections, a little bit? Do. You have any patient
testimonials to share with us? Kristine: I can tell you, I’ve
had patients cry on the phone and call back and say this has
changed. My life.
“You have saved my marriage.. This has saved our
” So those kinds of testimonies from patients. Are,
You know, just make it all worth: it. You know, because they’re
coming to us out of desperation when nothing has else has
worked. And they’re, looking for help. And, so that we can give
them back their sexual life. Back. It’s…, it’s life, changing
for them., Savannah: And, with that, what
would, you say, statistically,. What is the success rate? Of
These, treatments?, Kristine:, 90%, Savannah:, 90%, Wow,, Kristine: That’s, pretty high.
Yeah,. We can treat most men. You know,. The next step would be a
penile implant through their local urologist/surgeon,, but 90%
of. The time, we’re able to give men an… you know, an adequate
sex life, or one that they’re happy. With. Now, these…, a 70
year old man may not have a 21 year old erection, again., I, don’t
want them to,. You know, get unrealistic expectations, but it
should be a,. You know, a firm enough direction that they’re
able to engage in and be happy with. And, that’s what we want. James: Yeah. Yeah. Have you had
any people cry, like out of out of pain on the phone? Kristine: No, I haven’t. Savannah: No,, like I’m doing it
right. Now. We’re on the phone. No. Kristine: Good. Now, there are
patients that don’t follow the instructions and they inject
improperly and they may,. You know, have some issues that way.
Yeah. But. We provide very good,. You know, instruction and video
for them, for them to feel comfortable about giving their
injection properly. James: Well, speaking of
foolproof methods of erectile dysfunction. Meds, tell us about
the oral medications. I know, there’s sildenafil and tadalafil
is that how they pronounce it Kristine: Yeah, tadalafil, /
sildenafil,, Viagra, / Cialis, for patients that you know, know of
it by their trade name. Kristine: But, those medications
are great,. They are systemic,, so James:. Okay, they go through your entire
body.. They can interfere with a patient’s own medication, lists
such as high blood pressure medications or some of their
components of treating the high blood pressure,. So they’re not
for, everyone. The other thing is,. Is they don’t always work
for everyone,, which is why there is an injectable. But the
statistics show that about 75% of men who use an oral
sildenafil tadalafil get good results,. So that’s it’s a
high…! It’s a high number., James: But, that’s a C and try
mix has a, is an A Kristine: That’s right. You got
it. That’s right. And. Some some men get good results with using
it,, but they have headaches, and stuffy nose, and blurred vision,
and the side effects for some of those can be debilitating. For
Our, men. Yes,, just not. Savannah: If. We could go back on
again with the injections. Is there side effects with those as
well? Kristine: Side effects from the
injection can be very…. It’s really very low. Because. We are
just treating the erection, only. The metabolism of the medication
is really done at the site. And. So if they are injecting
properly, and their medication is of the right dose, usually
you’re getting a good firm, erection…, adequate duration.
Some men will develop a priapism, which is an erection
longer than four hours,, in which case we have a safety precaution
for them. There is an antidote that they can inject… will
bring their erection, down. But I would tell you that most often
it doesn’t happen in our patients, because they’re
following good direction., Savannah: Okay. So it’s
important to take your advice. Kristine: That’s right. Don’t
over, inject. Don’t,, you know,, you don’t want to just go at it
alone.. James: Yeah, don’t take Viagra
and an injection at the same time. Kristine: That’s, right. Yeah.
Yeah, one or the other. Savannah: Could you take them
together? What would happen? James: Yeah, good question., Kristine: You would develop a
priapism. Most likely. You would have a four hour. Erection. So it
isn’t advised that they take them. Together. One or the other. Savannah: Okay. Well,, with all
of this, I wanted to talk a little bit about libido because
that is an important factor in all of this. So. What are some of
the available? Libido treatments out, there? Or, maybe libido
medications? Kristine: Okay,, so we’ve got a
couple treatments for libido and one is FDA approved for women
for low libido and we’ve got PT-141,, which is great. Because
These are not for the vascular system,. They work on the nervous
system. So. They talk to your brain basically, to spit out
more dopamine that helps with desire and sexual activity.
Helps with erection firmness. Too. The nice thing about these
is that you just take them as needed. Basis. They come in a
nas al spray or an injectable,, not a penile injectable though,
just, a subcutaneous injectable. Savannah: Can, you tell me: what
subcutaneous is Kristine: Just right, underneath
your, skin Savannah:, Oh, okay, Kristine: So. You can do your
abdomen, your hip,, your buttock area. So, it’s not a penile
injectable, and some patients would rather start there.. And,
You know, see how they do with that. So yeah. Savannah: Yeah.. So those libido
medications that you were talking, about. Do, those work
with men as well? Kristine:, That’s, right., Both men
and women on both those medications can be used, for
both., Savannah: Okay,, so it definitely
is… So. The PT-141 can be used, maybe at the same time, if
they’re planning on having sex? Kristine: You can,. You can take
PT-141 prior to engaging, like an hour before. Usually the
onset is within that hour. And. It lasts between two and four hours. Savannah: Okay. Kristine: So. It’s kind of a nice
length of time. James: So. It just gives you the
desire Kristine: Helps, with desire.
Spits out, yeah,, more dopamine,, James:, So If. You have like
healthy erectile function,, then it, but you just have like a low
sex drive, then… James: Help with that, Okay. Kristine: Right. Kristine: Absolutely. James: Cool., Yeah. So. You can I
mean,, so you have like a whole menu of options that we have a
healthy sex, life., Kristine: Well,. We have good
treatment speCialists too, that you can call in and talk to
them, and they can really formulate a good plan for you,
before. It goes to the provider for them to even further talk
clinically for you. Savannah: Wow. The last thing. On
My list here is something called oxytocin. Spray. Can, you just
tell us a little bit about that. As well? Kristine: Yeah. Oxytocin is a
peptide. You know,, it’s used in labor and delivery to induce
contractions. So. It is used for that. But. What we’ve found is,
is that it also helps with… …. It’s a cuddle, hormone, is
what. We call it. So. It helps with libido and desire. And it
works as a nasal spray. Yeah,. Nasal spray is what we have
available currently for that. Savannah: A, nasal spray,. So it’s
nothing like nothing like the injections, Kristine: No, injection., James: So. It’s a spray., So it
could be a like a love, potion. So. If you wanted a woman to be
attracted to you spray her without her knowing. Right? Kristine: That’s right
(sarcasm). You could try. That. James: I won’t try it. Kristine:, Okay, James: But, some people, could.
Yeah Kristine: Somebody, could That would be an interesting
experiment. Savannah: Would that really
work, though? Kristine: No, no,. It has to be
systemically. James: She’s not allowed to say
it. Would work. Kristine: So… So yeah, in the
same way that PT-141, you would you give it about an hour prior
and onset… A little bit, less. Probably about two hours: for… James:, So spray, her an hour
early., Savannah: Spray, her an hour
early., Kristine:, Both, men and women.
And. You can use that in conjunction with other
treatments too. So. Those are nice.. Those are stackable…
what. We call stackable medications that you can use
with something like a Viagra, Cialis or an injectable. Savannah: Okay,, so it can be
used on top of other medications. Is, that Is it
addictive at all? When you when I hear oxytocin? I, think of oxycontin? James: Yeah, same., Kristine: Oh,, totally different James: isn’t the same. Spelling. Kristine: No, oxytocin is a
natural hormone. So no,, not addicting. Any of these
medications, really, If, you use them. You’ll get an effect and
benefit from them. If. You don’t,, there’s no wean down or
dependency issues with any of those. James: Sorry,. You said you said
wean down and I thought… That’s, the opposite of what
we’re. Trying to accomplish… Savannah: That would be the
antidote. James:, Yeah, yeah, exactly.
That’s. What you should call it., So yeah,, what what ED
medications does Invigor Medical, offer? Kristine: Everything, that we’ve
talked about today we offer. So, you are able to just jump on if
you, want to read more about any of those medications, or
supplements and think any of them could be right for you.. If
You want to call in, chat in, with our treatment. SpeCialists,
They would be happy to to help you as well. And, so we offer
everything we’ve talked about today. James:, Okay, Savannah:, Great! Christine,
thank, you so,, so much for joining us., You’re, just a wealth
of information, and we really appreciate it. Kristine: Thank you for having
me. Yeah, I really enjoyed coming on.

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